Depolymerization of Heparin Benzyl Ester in a Flow System

The preparation of enoxaparin via the base-promoted depolymerization of heparin is well known. In this paper, we present our efforts to convert this preparation into a flow method. Streams of base and ester solutions are combined and heated in a flow reactor, and the variations in flow rate, tempera...

Full description

Bibliographic Details
Main Authors: Richard T. Taylor, Rebecca G. Brunner
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Chemistry Proceedings
Subjects:
Online Access:https://www.mdpi.com/2673-4583/12/1/64