Reactive Oxygen Species, Superoxide Dimutases, and PTEN-p53-AKT-MDM2 Signaling Loop Network in Mesenchymal Stem/Stromal Cells Regulation

Reactive Oxygen Species, Superoxide Dimutases, and PTEN-p53-AKT-MDM2 Signaling Loop Network in Mesenchymal Stem/Stromal Cells Regulation

Mesenchymal stromal/stem cells (MSCs) are multipotent cells that can differentiate to various specialized cells, which have the potential capacity to differentiate properly and accelerate recovery in damaged sites of the body. This stem cell technology has become the fundamental element in regenerat...

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Bibliographic Details
Main Authors: Satoru Matsuda, Yukie Nakagawa, Yasuko Kitagishi, Atsuko Nakanishi, Toshiyuki Murai
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Cells
Subjects:
p53
PTEN
AKT
MDM2
superoxide dismutase
SOD
reactive oxygen species
ROS
mesenchymal stromal/stem cell
MSC
stemness
Online Access:http://www.mdpi.com/2073-4409/7/5/36

Internet

http://www.mdpi.com/2073-4409/7/5/36

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