Conformational study of 3-acety 1-2, 7, 7-trimethyl-4-phenyl- 1,4,S,6, 7,8-hexahydro-5-quinolone starting from the crystallographics datas
1,4-dihydropyridine (1,4-DHPs) are well known compounds as a consequence of their pharmacological profile as calcium channel modulator. The chemical modifications carried out on the DHP ring such as the presence of different substituents have allowed expansion of the structure activity relationship...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Centro Nacional de Investigaciones Científicas
2000-06-01
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Series: | Revista CENIC Ciencias Químicas |
Online Access: | https://revista.cnic.cu/index.php/RevQuim/article/view/1739 |