Comparative genomics of the Western Hemisphere soft tick-borne relapsing fever borreliae highlights extensive plasmid diversity

Comparative genomics of the Western Hemisphere soft tick-borne relapsing fever borreliae highlights extensive plasmid diversity

Abstract Background Tick-borne relapsing fever (TBRF) is a globally prevalent, yet under-studied vector-borne disease transmitted by soft and hard bodied ticks. While soft TBRF (sTBRF) spirochetes have been described for over a century, our understanding of the molecular mechanisms facilitating vect...

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Bibliographic Details
Main Authors: Alexander R. Kneubehl, Aparna Krishnavajhala, Sebastián Muñoz Leal, Adam J. Replogle, Luke C. Kingry, Sergio E. Bermúdez, Marcelo B. Labruna, Job E. Lopez
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Genomics
Subjects:
Relapsing fever
Borrelia
Comparative genomics
Plasmids
Microbial genomics
Long-read sequencing
Online Access:https://doi.org/10.1186/s12864-022-08523-7

Internet

https://doi.org/10.1186/s12864-022-08523-7

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