Evaluation of the effects of ascorbic acid on metabolism of human mesenchymal stem cells

Evaluation of the effects of ascorbic acid on metabolism of human mesenchymal stem cells

Abstract Background Mesenchymal stem cells (MSCs) are multipotent cells holding much promise for applications in regenerative medicine. However, with problems such as aging, increases in heteroploid cells, genomic instability, and reduced maintenance of stemness, more stable culturing methods and th...

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Bibliographic Details
Main Authors: Koichi Fujisawa, Kazusa Hara, Taro Takami, Sae Okada, Toshihiko Matsumoto, Naoki Yamamoto, Isao Sakaida
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Stem Cell Research & Therapy
Subjects:
Ascorbic acid
Mesenchymal stem cell
Meztabolome
Transcriptome
Extracellular matrix
Hypoxia
Online Access:http://link.springer.com/article/10.1186/s13287-018-0825-1

Internet

http://link.springer.com/article/10.1186/s13287-018-0825-1

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