A shared mechanism for TNP-ATP recognition by members of the P2X receptor family

A shared mechanism for TNP-ATP recognition by members of the P2X receptor family

P2X receptors (P2X1–7) are non-selective cation channels involved in many physiological activities such as synaptic transmission, immunological modulation, and cardiovascular function. These receptors share a conserved mechanism to sense extracellular ATP. TNP-ATP is an ATP derivative acting as a no...

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Bibliographic Details
Main Authors: Xiao-Bo Ma, Chen-Xi Yue, Yan Liu, Yang Yang, Jin Wang, Xiao-Na Yang, Li-Dong Huang, Michael X. Zhu, Motoyuki Hattori, Chang-Zhu Li, Ye Yu, Chang-Run Guo
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Computational and Structural Biotechnology Journal
Subjects:
TNP-ATP
P2X3 receptor
P2X7 receptor
Recognition mechanism
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037023004774

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http://www.sciencedirect.com/science/article/pii/S2001037023004774

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