Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation

<p>Abstract</p> <p>It has been demonstrated that the p53 pathway plays an important role in HIV-1 infection. Previous work from our lab has established a model demonstrating how p53 could become inactivated in HIV-1 infected cells through binding to Tat. Subsequently, p53 was inact...

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Bibliographic Details
Main Authors: Dubrovsky Larisa, Dowd Cynthia S, Klase Zachary, Castro Iris, Zweier Lynnsey, Pedati Caitlin, Kehn-Hall Kylene, Wu Weilin, Bukrinsky Michael, Kashanchi Fatah
Format: Article
Language:English
Published: BMC 2008-03-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/5/1/41