Activation of Gαq sequesters specific transcripts into Ago2 particles

Abstract The Gαq/phospholipase Cβ1 (PLCβ1) signaling system mediates calcium responses from hormones and neurotransmitters. While PLCβ1 functions on the plasma membrane, there is an atypical cytosolic population that binds Argonaute 2 (Ago2) and other proteins associated with stress granules prevent...

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Bibliographic Details
Main Authors: Lela Jackson, Madison Rennie, Alison Poussaint, Suzanne Scarlata
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-12737-w