mosGILT controls innate immunity and germ cell development in Anopheles gambiae

mosGILT controls innate immunity and germ cell development in Anopheles gambiae

Abstract Gene-edited mosquitoes lacking a gamma-interferon-inducible lysosomal thiol reductase-like protein, namely (mosGILT null ) have lower Plasmodium infection, which is linked to impaired ovarian development and immune activation. The transcriptome of mosGILT null Anopheles gambiae was therefor...

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Bibliographic Details
Main Authors: Gunjan Arora, Xiaotian Tang, Yingjun Cui, Jing Yang, Yu-Min Chuang, Jayadev Joshi, Andaleeb Sajid, Yuemei Dong, Peter Cresswell, George Dimopoulos, Erol Fikrig
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Genomics
Subjects:
Anopheles
Mosquito
Immunity
Metabolism
Genomics
Ovarian Development
Online Access:https://doi.org/10.1186/s12864-023-09887-0

Internet

https://doi.org/10.1186/s12864-023-09887-0

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