Role of PI3K/Akt Signaling in Memory CD8 T Cell Differentiation

The clonal expansion, differentiation into effectors and establishing an immunological memory are crucial components of the adaptive immune response. Following the initial encounter with a pathogen, clonal CD8 T cell expansion yields at least two distinct populations of effector cells, short-lived e...

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Bibliographic Details
Main Authors: Eui Ho eKim, M eSuresh
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00020/full