Intestinal Region-Specific and Layer-Dependent Induction of TNFα in Rats with Streptozotocin-Induced Diabetes and after Insulin Replacement

Intestinal Region-Specific and Layer-Dependent Induction of TNFα in Rats with Streptozotocin-Induced Diabetes and after Insulin Replacement

Tumour necrosis factor alpha (TNFα) is essential in neuroinflammatory modulation. Therefore, the goal of this study is to reveal the effects of chronic hyperglycaemia and insulin treatment on TNFα expression in different gut segments and intestinal wall layers. TNFα expression was mapped by fluoresc...

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Bibliographic Details
Main Authors: Nikolett Bódi, Lalitha Chandrakumar, Afnan al Doghmi, Diána Mezei, Zita Szalai, Bence Pál Barta, János Balázs, Mária Bagyánszki
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
tumour necrosis factor alpha
cytokine
myenteric neurons
neuronal environment
duodenum
ileum
Online Access:https://www.mdpi.com/2073-4409/10/9/2410

Internet

https://www.mdpi.com/2073-4409/10/9/2410

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