CPT2 down-regulation promotes tumor growth and metastasis through inducing ROS/NFκB pathway in ovarian cancer

CPT2 down-regulation promotes tumor growth and metastasis through inducing ROS/NFκB pathway in ovarian cancer

Background: Carnitine palmitoyltransferase 2 (CPT2) is a rate-limiting enzyme involved in fatty acid β-oxidation (FAO) regulation. Recently, it has been increasingly recognized that lipid metabolism dysregulation is closely implicated in tumorigenesis. However, the involvement of CPT2 in the progres...

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Bibliographic Details
Main Authors: Xiaohong Zhang, Zhen Zhang, Shujuan Liu, Jia Li, Liying Wu, Xiaohui Lv, Jia Xu, Biliang Chen, Shuhua Zhao, Hong Yang
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Translational Oncology
Subjects:
Carnitine palmitoyltransferase 2
Growth
Metastasis
Glycolysis
Ovarian cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523321000152

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http://www.sciencedirect.com/science/article/pii/S1936523321000152

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