Synthesis, Anti-Influenza H1N1 and Anti-Dengue Activity of A-Ring Modified Oleanonic Acid Polyamine Derivatives

Synthesis, Anti-Influenza H1N1 and Anti-Dengue Activity of A-Ring Modified Oleanonic Acid Polyamine Derivatives

A series of sixteen A-ring modified (2,3-indolo-, 2-benzylidene) oleanonic acid derivatives, holding some cyclic amines, linear polyamines and benzylaminocarboxamides at C28, has been synthesized and screened for antiviral activity against influenza A/PuertoRico/8/34 (H1N1) and Dengue virus serotype...

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Bibliographic Details
Main Authors: Irina Smirnova, Anastasiya Petrova, Gul’nara Giniyatullina, Anna Smirnova, Alexandrina Volobueva, Julia Pavlyukova, Vladimir Zarubaev, Tran Van Loc, Thao Tran Thi Phoung, Vu Thi Bich Hau, Nguyen Thi Thu Thuy, Myint Myint Khine, Oxana Kazakova
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
triterpenoids
oleanolic acid
polyamine
Ugi derivatives
indole
benzylidene
Online Access:https://www.mdpi.com/1420-3049/27/23/8499

Internet

https://www.mdpi.com/1420-3049/27/23/8499

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