Mitochondrial phenotypes in purified human immune cell subtypes and cell mixtures

Mitochondrial phenotypes in purified human immune cell subtypes and cell mixtures

Using a high-throughput mitochondrial phenotyping platform to quantify multiple mitochondrial features among molecularly defined immune cell subtypes, we quantify the natural variation in mitochondrial DNA copy number (mtDNAcn), citrate synthase, and respiratory chain enzymatic activities in human n...

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Bibliographic Details
Main Authors: Shannon Rausser, Caroline Trumpff, Marlon A McGill, Alex Junker, Wei Wang, Siu-Hong Ho, Anika Mitchell, Kalpita R Karan, Catherine Monk, Suzanne C Segerstrom, Rebecca G Reed, Martin Picard
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-10-01
Series:eLife
Subjects:
mitochondria
leukocytes
sexual dimorphism
aging
dynamic variation
immunometabolism
Online Access:https://elifesciences.org/articles/70899

Internet

https://elifesciences.org/articles/70899

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