Innate immunity and effector and regulatory mechanisms involved in allergic contact dermatitis

Abstract: Skin's innate immunity is the initial activator of immune response mechanisms, influencing the development of adaptive immunity. Some contact allergens are detected by Toll-like receptors (TLRs) and inflammasome NLR3. Keratinocytes participate in innate immunity and, in addition to fu...

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Bibliographic Details
Main Authors: Marilene Chaves Silvestre, Maria Notomi Sato, Vitor Manoel Silva dos Reis
Format: Article
Language:English
Published: Sociedade Brasileira de Dermatologia 2018-03-01
Series:Anais Brasileiros de Dermatologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962018000200242&tlng=en