Global assessment of genomic regions required for growth in Mycobacterium tuberculosis.

Identifying genomic elements required for viability is central to our understanding of the basic physiology of bacterial pathogens. Recently, the combination of high-density mutagenesis and deep sequencing has allowed for the identification of required and conditionally required genes in many bacter...

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Bibliographic Details
Main Authors: Yanjia J Zhang, Thomas R Ioerger, Curtis Huttenhower, Jarukit E Long, Christopher M Sassetti, James C Sacchettini, Eric J Rubin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3460630?pdf=render