Targeting alveolar macrophages shows better treatment response than deletion of interstitial macrophages in EGFR mutant lung adenocarcinoma

Targeting alveolar macrophages shows better treatment response than deletion of interstitial macrophages in EGFR mutant lung adenocarcinoma

Abstract Introduction Alveolar macrophages (AMs) are critical in the development of lung adenocarcinoma driven by epidermal growth factor receptor (EGFR) mutations. Whether interstitial macrophages (IMs) are also involved in lung tumorigenesis is still unclear. Thus, the aim of this study is to eval...

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Bibliographic Details
Main Authors: Kristina Alikhanyan, Yuanyuan Chen, Simone Kraut, Rocio Sotillo
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Immunity, Inflammation and Disease
Subjects:
alveolar macrophages
clodronate liposomes
EGFR mutation
interstitial macrophages
lung cancer
Online Access:https://doi.org/10.1002/iid3.293

Internet

https://doi.org/10.1002/iid3.293

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