Understanding NF‐κB signaling via mathematical modeling

Abstract Mammalian inflammatory signaling, for which NF‐κB is a principal transcription factor, is an exquisite example of how cellular signaling pathways can be regulated to produce different yet specific responses to different inflammatory insults. Mathematical models, tightly linked to experiment...

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Bibliographic Details
Main Authors: Raymond Cheong, Alexander Hoffmann, Andre Levchenko
Format: Article
Language:English
Published: Springer Nature 2008-05-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.1038/msb.2008.30