Transcriptome Analysis Identifies Doublesex and Mab-3 Related Transcription Factor (DMRT3) in Nasal Polyp Epithelial Cells of Patients Suffering from Non-Steroidal Anti-Inflammatory Drug-Exacerbated Respiratory Disease (AERD)

Transcriptome Analysis Identifies Doublesex and Mab-3 Related Transcription Factor (DMRT3) in Nasal Polyp Epithelial Cells of Patients Suffering from Non-Steroidal Anti-Inflammatory Drug-Exacerbated Respiratory Disease (AERD)

Background: Aspirin-exacerbated respiratory disease (AERD) is a syndrome characterised by chronic rhinosinusitis, nasal polyps, asthma and aspirin intolerance. An imbalance of eicosanoid metabolism with anover-production of cysteinyl leukotrienes (CysLTs) has been associated with AERD. However, the...

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Bibliographic Details
Main Authors: V.S. Priyadharshini, Marcos Alejandro Jiménez-Chobillon, Jos de Graaf, Raúl Porras Gutiérrez de Velasco, Christina Gratziou, Fernando Ramírez-Jiménez, Luis M. Teran
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomolecules
Subjects:
Aspirin-exacerbated respiratory disease
DMRT3
epithelial cells
nasal airway
nasal polyps
transcriptome analysis
Online Access:https://www.mdpi.com/2218-273X/11/8/1092

Internet

https://www.mdpi.com/2218-273X/11/8/1092

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