Plasma glial fibrillary acidic protein and neurofilament light chain for the diagnostic and prognostic evaluation of frontotemporal dementia

Abstract Background Astrocytes play an essential role in neuroinflammation and are involved in the pathogenesis of neurodenegerative diseases. Studies of glial fibrillary acidic protein (GFAP), an astrocytic damage marker, may help advance our understanding of different neurodegenerative diseases. I...

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Main Authors: Nuole Zhu, Miguel Santos-Santos, Ignacio Illán-Gala, Victor Montal, Teresa Estellés, Isabel Barroeta, Miren Altuna, Javier Arranz, Laia Muñoz, Olivia Belbin, Isabel Sala, Maria Belén Sánchez-Saudinós, Andrea Subirana, Laura Videla, Jordi Pegueroles, Rafael Blesa, Jordi Clarimón, Maria Carmona-Iragui, Juan Fortea, Alberto Lleó, Daniel Alcolea
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Translational Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s40035-021-00275-w