Pharmacology and clinical potential of guanylyl cyclase C agonists in the treatment of ulcerative colitis

Giovanni M Pitari Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, USA Abstract: Agonists of the transmembrane intestinal receptor guanylyl cyclase C (GCC) have recently attracted interest as promising human therapeutics. Peptide ligands that c...

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Bibliographic Details
Main Author: Pitari GM
Format: Article
Language:English
Published: Dove Medical Press 2013-04-01
Series:Drug Design, Development and Therapy
Online Access:http://www.dovepress.com/pharmacology-and-clinical-potential-of-guanylyl-cyclase-c-agonists-in--a12820