Pharmacology and clinical potential of guanylyl cyclase C agonists in the treatment of ulcerative colitis
Giovanni M Pitari Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA, USA Abstract: Agonists of the transmembrane intestinal receptor guanylyl cyclase C (GCC) have recently attracted interest as promising human therapeutics. Peptide ligands that c...
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Format: | Article |
Language: | English |
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Dove Medical Press
2013-04-01
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Series: | Drug Design, Development and Therapy |
Online Access: | http://www.dovepress.com/pharmacology-and-clinical-potential-of-guanylyl-cyclase-c-agonists-in--a12820 |