Case report: A novel compound heterozygous variant in the TNXB gene causes single kidney agenesis and vesicoureteral reflux

Case report: A novel compound heterozygous variant in the TNXB gene causes single kidney agenesis and vesicoureteral reflux

Primary vesicoureteral reflux (VUR) is the prevailing congenital anomaly of the kidneys and urinary tract, posing a significant risk for pyelonephritis scarring and chronic renal insufficiency in pediatric patients. Nevertheless, the precise genetic etiology of VUR remains enigmatic. In this current...

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Bibliographic Details
Main Authors: Lei Liang, Haotian Wu, Haixia Meng, Lin Fu, Jianrong Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Endocrinology
Subjects:
vesicoureteral reflux
TNXB
compound heterozygous variant
single kidney
molecular dynamics
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1322395/full

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https://www.frontiersin.org/articles/10.3389/fendo.2024.1322395/full

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