Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts

Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts

Aims: Endothelial dysfunction plays a pivotal role in atherosclerosis, but the detailed mechanism remains incomplete understood. Nogo-B is an endoplasmic reticulum (ER)-localized protein mediating ER-mitochondrial morphology. We previously showed endothelial Nogo-B as a key regulator of endothelial...

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Bibliographic Details
Main Authors: Yu Zhang, Jing-Jing Li, Rui Xu, Xin-Pei Wang, Xin-Yi Zhao, Yuan Fang, Yu-Peng Chen, Shan Ma, Xiao-Hui Di, Wei Wu, Gang She, Zheng-Da Pang, Yi-Dong Wang, Xing Zhang, Wenjun Xie, Xiu-Ling Deng, Xiao-Jun Du, Yi Zhang
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Redox Biology
Subjects:
Nogo-B
Pressure overload
Mitochondria
Reactive oxygen species
Coronary atherosclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723003452

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http://www.sciencedirect.com/science/article/pii/S2213231723003452

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