Human Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells: Current Controversies

Human Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells: Current Controversies

Brain microvascular endothelial cells (BMECs) possess unique properties that are crucial for many functions of the blood-brain-barrier (BBB) including maintenance of brain homeostasis and regulation of interactions between the brain and immune system. The generation of a pure population of putative...

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Bibliographic Details
Main Authors: Tyler M. Lu, José Gabriel Barcia Durán, Sean Houghton, Shahin Rafii, David Redmond, Raphaël Lis
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Physiology
Subjects:
induced pluripotent stem cells
endothelial cell
epithelial cell
cell fate and differentiation
misclassification
brain–blood barrier (BBB)
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.642812/full

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https://www.frontiersin.org/articles/10.3389/fphys.2021.642812/full

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