The biophysical principles underpinning muco-trapping functions of antibodies

In addition to the classical immunological functions such as neutralization, antibody-dependent cellular cytotoxicity, and complement activation, IgG antibodies possess a little-recognized and under-utilized effector function at mucosal surfaces: trapping pathogens in mucus. IgG can potently immobil...

Full description

Bibliographic Details
Main Authors: Alison Schaefer, Samuel K. Lai
Format: Article
Language:English
Published: Taylor & Francis Group 2022-04-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2021.1939605