Protein Dimerization Generates Bistability in Positive Feedback Loops
Bistability plays an important role in cellular memory and cell-fate determination. A positive feedback loop can generate bistability if it contains ultrasensitive molecular reactions. It is often difficult to detect bistability based on such molecular mechanisms due to its intricate interaction wit...
Main Authors: | Chieh Hsu, Vincent Jaquet, Mumun Gencoglu, Attila Becskei |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2016-08-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124716308415 |
Similar Items
-
A positive mechanobiological feedback loop controls bistable switching of cardiac fibroblast phenotype
by: Lele Niu, et al.
Published: (2022-09-01) -
Bistability, probability transition rate and first-passage time in an autoactivating positive-feedback loop.
by: Xiu-Deng Zheng, et al.
Published: (2011-01-01) -
Different effects of redundant feedback loops on a bistable switch.
by: Domingo-Sananes, MR, et al.
Published: (2010) -
Consecutive Positive Feedback Loops Create a Bistable Switch that Controls Preadipocyte-to-Adipocyte Conversion
by: Byung Ouk Park, et al.
Published: (2012-10-01) -
Spatial epigenetic control of mono- and bistable gene expression.
by: János Z Kelemen, et al.
Published: (2010-03-01)