Early malaria infection, dysregulation of angiogenesis, metabolism and inflammation across pregnancy, and risk of preterm birth in Malawi: A cohort study.

Early malaria infection, dysregulation of angiogenesis, metabolism and inflammation across pregnancy, and risk of preterm birth in Malawi: A cohort study.

BACKGROUND:Malaria in pregnancy is associated with adverse birth outcomes. However, the underlying mechanisms remain poorly understood. Tight regulation of angiogenic, metabolic, and inflammatory pathways are essential for healthy pregnancies. We hypothesized that malaria disrupts these pathways lea...

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Bibliographic Details
Main Authors: Robyn E Elphinstone, Andrea M Weckman, Chloe R McDonald, Vanessa Tran, Kathleen Zhong, Mwayiwawo Madanitsa, Linda Kalilani-Phiri, Carole Khairallah, Steve M Taylor, Steven R Meshnick, Victor Mwapasa, Feiko O Ter Kuile, Andrea L Conroy, Kevin C Kain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1002914

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https://doi.org/10.1371/journal.pmed.1002914

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