Treatment with analgesics after mouse sciatic nerve injury does not alter expression of wound healing-associated genes

Treatment with analgesics after mouse sciatic nerve injury does not alter expression of wound healing-associated genes

Animal models of sciatic nerve injury are commonly used to study neuropathic pain as well as axon regeneration. Administration of post-surgical analgesics is an important consideration for animal welfare, but the actions of the analgesic must not interfere with the scientific goals of the experiment...

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Bibliographic Details
Main Authors: Matt C Danzi, Dario Motti, Donna L Avison, John L Bixby, Vance P Lemmon
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Neural Regeneration Research
Subjects:
acetaminophen; analgesics; axon; buprenorphine; dorsal root ganglia; gene expression; peripheral nerve injuries; regeneration; sciatic nerve; wound healing
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=1;spage=144;epage=149;aulast=Danzi

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=1;spage=144;epage=149;aulast=Danzi

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