Comparison of Serum Pharmacodynamic Biomarkers in Prednisone-Versus Deflazacort-Treated Duchenne Muscular Dystrophy Boys

Comparison of Serum Pharmacodynamic Biomarkers in Prednisone-Versus Deflazacort-Treated Duchenne Muscular Dystrophy Boys

Prednisone (Pred) and Deflazacort (Dfz) are commonly used glucocorticoids (GCs) for Duchenne muscular dystrophy (DMD) treatment and management. While GCs are known to delay the loss of ambulation and motor abilities, chronic use can result in onerous side effects, e.g., weight gain, growth stunting,...

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Bibliographic Details
Main Authors: Shefa Tawalbeh, Alison Samsel, Heather Gordish-Dressman, Yetrib Hathout, CINRG-DNHS Investigators, Utkarsh J. Dang
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Journal of Personalized Medicine
Subjects:
Duchenne muscular dystrophy
pharmacodynamic biomarkers
prednisone
deflazacort
glucocorticoids
corticosteroids
Online Access:https://www.mdpi.com/2075-4426/10/4/164

Internet

https://www.mdpi.com/2075-4426/10/4/164

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