miR-200b downregulates CFTR during hypoxia in human lung epithelial cells

miR-200b downregulates CFTR during hypoxia in human lung epithelial cells

Abstract Background Hypoxic conditions induce the expression of hypoxia-inducible factors (HIFs) that allow cells to adapt to the changing conditions and alter the expression of a number of genes including the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is a low abundance mRNA i...

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Bibliographic Details
Main Authors: Sylwia Bartoszewska, Wojciech Kamysz, Bogdan Jakiela, Marek Sanak, Jarosław Króliczewski, Zsuzsa Bebok, Rafal Bartoszewski, James F. Collawn
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Cellular & Molecular Biology Letters
Subjects:
CFTR
HIF-1
micro-RNA 200b
hsa-miR-200b-3p
Online Access:http://link.springer.com/article/10.1186/s11658-017-0054-0

Internet

http://link.springer.com/article/10.1186/s11658-017-0054-0

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