Gene Expression in Spontaneous Experimental Autoimmune Encephalomyelitis Is Linked to Human Multiple Sclerosis Risk Genes

Gene Expression in Spontaneous Experimental Autoimmune Encephalomyelitis Is Linked to Human Multiple Sclerosis Risk Genes

Recent genome-wide association studies have identified over 230 genetic risk loci for multiple sclerosis. Current experimental autoimmune encephalomyelitis (EAE) models requiring active induction of disease may not be optimally suited for the characterization of the function of these genes. We have...

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Bibliographic Details
Main Authors: Hans Faber, Dunja Kurtoic, Gurumoorthy Krishnamoorthy, Peter Weber, Benno Pütz, Bertram Müller-Myhsok, Frank Weber, Till F. M. Andlauer
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
experimental autoimmune encephalomyelitis (EAE)
myelin oligodendrocyte glycoprotein (MOG)
T helper cell (Th)
multiple sclerosis
risk genes
gene expression
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02165/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.02165/full

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