Analysis of the Role of Stellate Cell VCAM-1 in NASH Models in Mice

Analysis of the Role of Stellate Cell VCAM-1 in NASH Models in Mice

Non-alcoholic fatty liver disease (NAFLD) can progress to non-alcoholic steatohepatitis (NASH), characterized by inflammation and fibrosis. Fibrosis is mediated by hepatic stellate cells (HSC) and their differentiation into activated myofibroblasts; the latter process is also promoted by inflammatio...

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Bibliographic Details
Main Authors: Kyoung-Jin Chung, Aigli-Ioanna Legaki, Grigorios Papadopoulos, Bettina Gercken, Janine Gebler, Robert F. Schwabe, Triantafyllos Chavakis, Antonios Chatzigeorgiou
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
non-alcoholic fatty liver disease (NAFLD)
non-alcoholic steatohepatitis (NASH)
hepatic stellate cells (HSCs)
vascular cell adhesion molecule 1 (VCAM-1)
Online Access:https://www.mdpi.com/1422-0067/24/5/4813

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https://www.mdpi.com/1422-0067/24/5/4813

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