Circulating Growth Differentiation Factor 15 Is Increased Preceding Preeclampsia Diagnosis: Implications as a Disease Biomarker

Circulating Growth Differentiation Factor 15 Is Increased Preceding Preeclampsia Diagnosis: Implications as a Disease Biomarker

Background We investigated the biomarker potential of growth differentiation factor 15 (GDF‐15), a stress response protein highly expressed in placenta, to predict preeclampsia. Methods and Results In 2 prospective cohorts (cohort 1: 960 controls, 39 women who developed preeclampsia; cohort 2: 950 c...

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Bibliographic Details
Main Authors: Tess Cruickshank, Teresa M. MacDonald, Susan P. Walker, Emerson Keenan, Kirsten Dane, Anna Middleton, Valerie Kyritsis, Jenny Myers, Catherine Cluver, Roxanne Hastie, Lina Bergman, Damanpreet Garcha, Ping Cannon, Elizabeth Murray, Tuong‐Vi Nguyen, Richard Hiscock, Natasha Pritchard, Natalie J. Hannan, Stephen Tong, Tu’uhevaha J. Kaitu’u‐Lino
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
biomarker
placental growth factor
preeclampsia
pregnancy
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.020302

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.020302

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