Novel FOXM1 inhibitor STL001 sensitizes human cancers to a broad-spectrum of cancer therapies

Abstract Forkhead box protein M1 (FOXM1) is often overexpressed in human cancers and strongly associated with therapy resistance and less good patient survival. The chemotherapy options for patients with the most aggressive types of solid cancers remain very limited because of the acquired drug resi...

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Bibliographic Details
Main Authors: Sanjeev Raghuwanshi, Xu Zhang, Zarema Arbieva, Irum Khan, Hisham Mohammed, Z. Wang, Alexander Domling, Carlos Jaime Camacho, Andrei L. Gartel
Format: Article
Language:English
Published: Nature Publishing Group 2024-05-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01929-0