Intercellular adhesion mdecule-1 expression and dendritic cell distribution in lymphatic metastasis of colon cancer(结肠癌淋巴转移时细胞间粘附分子(ICAM-1)表达和树突状细胞分布)
用ICAM-1(Intercellular adhesion molecule-1)和S-100 免疫组织化学技术,Ishigami 分级记数和统计学分析方法,研究结肠癌淋巴转移时细胞间粘附分子-1在淋巴管内皮细胞中的表达和树突状细胞(Dendritic cells,DCs)的分布.正常结肠组织淋巴管内皮细胞ICAM-1表达阴性,癌组织淋巴管内皮细胞ICAM-1表达呈阳性.随着癌组织浸润深度的增加,ICAM-1阳性淋巴管数目逐渐增多(P<0.01).当肠周淋巴结有癌转移时,ICAM-1阳性淋巴管明显多于无癌转移组(p<0.01);与ICAM-1的表达相反,树突状细胞(DCs)局部浸...
| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Zhejiang University Press
2003-05-01
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| Series: | Zhejiang Daxue xuebao. Lixue ban |
| Subjects: | |
| Online Access: | https://doi.org/zjup/1008-9497.2003.30.3.327-331 |