Role of Whole-exome Sequencing in Phenotype Classification and Clinical Treatment of Pediatric Restrictive Cardiomyopathy

Role of Whole-exome Sequencing in Phenotype Classification and Clinical Treatment of Pediatric Restrictive Cardiomyopathy

Background: Restrictive cardiomyopathy (RCM) is the least common cardiomyopathy in which the walls are rigid and the heart is restricted from stretching and filling properly. Cardiac troponin I (cTnI) mutation-caused myofibril Ca2+ hypersensitivity has been shown to be associated with impaired diast...

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Bibliographic Details
Main Authors: Wen-Hong Ding, Ling Han, Yan-Yan Xiao, Ying Mo, Jing Yang, Xiao-Fang Wang, Mei Jin
Format: Article
Language:English
Published: Wolters Kluwer 2017-01-01
Series:Chinese Medical Journal
Subjects:
Pediatric Restrictive Cardiomyopathy; Phenotype Classification; TNNI3; Whole-exome Sequencing
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volume=130;issue=23;spage=2823;epage=2828;aulast=Ding

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http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volume=130;issue=23;spage=2823;epage=2828;aulast=Ding

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