Coupling of growth rate and developmental tempo reduces body size heterogeneity in C. elegans

Animals must reach the correct size during development, despite stochastic differences in their growth rate. Here, Stojanovski et al. show that a coupling of growth and development by an oscillatory timer buffers fluctuations in the growth of the nematode C. elegans to ensure its correct size.

Bibliographic Details
Main Authors: Klement Stojanovski, Helge Großhans, Benjamin D. Towbin
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-29720-8