Reduced osteoclast-derived apoptotic bodies in bone marrow characterizes the pathological progression of osteoporosis

Abstract Osteoporosis is associated with excessive activity of osteoclasts. In bone turn over, most osteoclasts undergo apoptosis after bone resorption and produce a large number of apoptotic bodies (ABs). However, the biological function of osteoclast-derived apoptotic bodies (OC-ABs) in the progre...

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Bibliographic Details
Main Authors: Yutong Wu, Hongbo Ai, Yuhang Xi, Pengbin Yin, Ying Qu, Jianzhong Xu, Ce Dou, Fei Luo
Format: Article
Language:English
Published: Nature Publishing Group 2023-04-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01434-w