FMLRC: Hybrid long read error correction using an FM-index

Abstract Background Long read sequencing is changing the landscape of genomic research, especially de novo assembly. Despite the high error rate inherent to long read technologies, increased read lengths dramatically improve the continuity and accuracy of genome assemblies. However, the cost and thr...

Full description

Bibliographic Details
Main Authors: Jeremy R. Wang, James Holt, Leonard McMillan, Corbin D. Jones
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2051-3