Probing the Influence of Linker Length and Flexibility in the Design and Synthesis of New Trehalase Inhibitors

Probing the Influence of Linker Length and Flexibility in the Design and Synthesis of New Trehalase Inhibitors

This work aims to synthesize new trehalase inhibitors selective towards the insect trehalase versus the porcine trehalase, in view of their application as potentially non-toxic insecticides and fungicides. The synthesis of a new pseudodisaccharide mimetic 8, by means of a stereoselective α-glucosyla...

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Bibliographic Details
Main Authors: Giampiero D’Adamio, Matilde Forcella, Paola Fusi, Paolo Parenti, Camilla Matassini, Xhenti Ferhati, Costanza Vanni, Francesca Cardona
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Molecules
Subjects:
iminosugars
trehalase inhibitors
pseudodisaccharides
pyrrolizidines
pyrrolidines
glycosylation reaction
Online Access:http://www.mdpi.com/1420-3049/23/2/436

Internet

http://www.mdpi.com/1420-3049/23/2/436

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