A novel loss-of-function mutation in NRAP is associated with left ventricular non-compaction cardiomyopathy

A novel loss-of-function mutation in NRAP is associated with left ventricular non-compaction cardiomyopathy

BackgroundThe nebulin-related-anchoring protein (NRAP) gene encodes actin-associated ankyrin. Few studies reported the association of the NRAP gene with cardiomyopathy. Thus, the genetic role of this gene in cardiomyopathy remains to be investigated.MethodsThe clinical data of the rare case of left...

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Bibliographic Details
Main Authors: Zhongman Zhang, Kangkang Xu, Lianfu Ji, Han Zhang, Jie Yin, Ming Zhou, Chunli Wang, Shiwei Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
cardiomyopathy
left ventricular non-compaction
NRAP
zebrafish
RNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1097957/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2023.1097957/full

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