Rapid reconstitution of ubiquitinated nucleosome using a non-denatured histone octamer ubiquitylation approach
Abstract Background Histone ubiquitination modification is emerging as a critical epigenetic mechanism involved in a range of biological processes. In vitro reconstitution of ubiquitinated nucleosomes is pivotal for elucidating the influence of histone ubiquitination on chromatin dynamics. Results I...
Main Authors: | , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-06-01
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Series: | Cell & Bioscience |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13578-024-01265-x |