Predicting stress response and improved protein overproduction in Bacillus subtilis

Abstract Bacillus subtilis is a well-characterized microorganism and a model for the study of Gram-positive bacteria. The bacterium can produce proteins at high densities and yields, which has made it valuable for industrial bioproduction. Like other cell factories, metabolic modeling of B. subtilis...

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Bibliographic Details
Main Authors: Juan D. Tibocha-Bonilla, Cristal Zuñiga, Asama Lekbua, Colton Lloyd, Kevin Rychel, Katie Short, Karsten Zengler
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-022-00259-0