Perspective: Controlling Epidermal Terminal Differentiation with Transcriptional Bursting and RNA Bodies

The outer layer of the skin, the epidermis, is the principal barrier to the external environment: post-mitotic cells terminally differentiate to form a tough outer cornified layer of enucleate and flattened cells that confer the majority of skin barrier function. Nuclear degradation is required for...

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Bibliographic Details
Main Authors: Duncan Wotherspoon, Clare Rogerson, Ryan F.L. O’Shaughnessy
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Journal of Developmental Biology
Subjects:
Online Access:https://www.mdpi.com/2221-3759/8/4/29