Differential effect of TLR2 and TLR4 on the immune response after immunization with a vaccine against Neisseria meningitidis or Bordetella pertussis.

Neisseria meningitidis and Bordetella pertussis are Gram-negative bacterial pathogens that can cause serious diseases in humans. N. meningitidis outer membrane vesicle (OMV) vaccines and whole cell pertussis vaccines have been successfully used in humans to control infections with these pathogens. T...

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Bibliographic Details
Main Authors: Floris Fransen, Rachel M Stenger, Martien C M Poelen, Harry H van Dijken, Betsy Kuipers, Claire J P Boog, Jos P M van Putten, Cécile A C M van Els, Peter van der Ley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3009743?pdf=render