Sildenafil in endotoxin-induced pulmonary hypertension: an experimental study

Sildenafil in endotoxin-induced pulmonary hypertension: an experimental study

Background: Sepsis and septic shock still represent great challenges in critical care medicine. Sildenafil has been largely used in the treatment of pulmonary arterial hypertension, but its effects in sepsis are unknown. The aim of this study was to investigate the hypothesis that sildenafil can att...

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Bibliographic Details
Main Authors: Daniella Aparecida Godoi Kemper, Denise Aya Otsuki, D..bora Rothstein Ramos Maia, Cristina de Oliveira Mossoco, Rog..rio Anderson Marcasso, Ligia Cristina C..mara Cunha, Jos.. Ot..vio Costa Auler, Jr., Denise Tabacchi Fantoni
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Brazilian Journal of Anesthesiology
Subjects:
Phosphodiesterase V inhibitors
Acute lung injury
LPS
Septic shock
Experimental model
Swine
Online Access:http://www.sciencedirect.com/science/article/pii/S0104001421002396

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http://www.sciencedirect.com/science/article/pii/S0104001421002396

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