Plasmid DNA Prime/Protein Boost Vaccination against <i>Campylobacter jejuni</i> in Broilers: Impact of Vaccine Candidates on Immune Responses and Gut Microbiota

Plasmid DNA Prime/Protein Boost Vaccination against <i>Campylobacter jejuni</i> in Broilers: Impact of Vaccine Candidates on Immune Responses and Gut Microbiota

<i>Campylobacter</i> infections, traced to poultry products, are major bacterial foodborne zoonoses, and vaccination is a potential solution to reduce these infections. In a previous experimental trial using a plasmid DNA prime/recombinant protein boost vaccine regimen, two vaccine candi...

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Bibliographic Details
Main Authors: Noémie Gloanec, Muriel Guyard-Nicodème, Raphaël Brunetti, Ségolène Quesne, Alassane Keita, Marianne Chemaly, Daniel Dory
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Pharmaceutics
Subjects:
systemic and mucosal immune response
antibodies
cytokines
β-defensins
<i>Campylobacter jejuni</i> caecal colonisation
caecal microbiota composition
Online Access:https://www.mdpi.com/1999-4923/15/5/1397

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https://www.mdpi.com/1999-4923/15/5/1397

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