Epigenetic regulation of Elf5 is associated with epithelial-mesenchymal transition in urothelial cancer.

E74-like factor 5 (Elf5) has been associated with tumor suppression in breast cancer. However, its role in urothelial cancer (UC) is completely unknown. Immunohistochemistry (IHC) and methylation specific PCR (MSP) were done to detect Elf5 expression level and its promoter methylation. Results revea...

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Bibliographic Details
Main Authors: Bo Wu, Xiaoming Cao, Xuezhi Liang, Xuhui Zhang, Wei Zhang, Guang Sun, Dongwen Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4309403?pdf=render