Low-level repressive histone marks fine-tune gene transcription in neural stem cells

Low-level repressive histone marks fine-tune gene transcription in neural stem cells

Coordinated regulation of gene activity by transcriptional and translational mechanisms poise stem cells for a timely cell-state transition during differentiation. Although important for all stemness-to-differentiation transitions, mechanistic understanding of the fine-tuning of gene transcription i...

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Bibliographic Details
Main Authors: Arjun Rajan, Lucas Anhezini, Noemi Rives-Quinto, Jay Y Chhabra, Megan C Neville, Elizabeth D Larson, Stephen F Goodwin, Melissa M Harrison, Cheng-Yu Lee
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-06-01
Series:eLife
Subjects:
Drosophila
neuroblast
Notch
polycomb repressive complex 2
asymmetric division
fine-tuning
Online Access:https://elifesciences.org/articles/86127

Internet

https://elifesciences.org/articles/86127

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