C188‐9 reduces TGF‐β1‐induced fibroblast activation and alleviates ISO‐induced cardiac fibrosis in mice

Cardiac fibrosis is the final event of heart failure and is associated with almost all forms of cardiovascular disease. Cardiac fibroblasts (CFs), a major cell type in the heart, are responsible for regulating normal myocardial function and maintaining extracellular matrix homeostasis in adverse myo...

Full description

Bibliographic Details
Main Authors: Jiao Liu, Yuxuan Jin, Bei Wang, Jinying Zhang, Shengkai Zuo
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.13212